I focus on the mechanism of lifespan extension and healthspan improvement exerted by different anti-aging treatments, such as dietary restriction and spermidine.

Techniques: drosophila genetics, confocal/STED microscopy, PCR, Western Blot, olfactory learning and memory, RNAseq & iTRAQ proteomics, mitochondrial (neuro)biology, autophagy, insect/murine cell cultures, gel electrophoresis, etc.

Liang Y, Sigrist S (2017): Autophagy and proteostasis in the control of synapse aging and disease. Current Opinion in Neurobiology (48):113-121

https://www.ncbi.nlm.nih.gov/pubmed/29274917